Nella scorsa edizione era arrivato a un passo dalla gloria, sconfitto in finale da Carlos Alcaraz (ATP 1), quest'anno l'avventura di Casper Ruud (5) agli US Open si è interrotta al secondo turno. Al termine di una battaglia di oltre tre ore, il norvegese ha ceduto il passo Zhizhen Zhang (67), capace di accedere per la seconda volta al terzo turno di un torneo del Grande Slam vincendo la sfida in cinque set, con i parziali di 6-4 5-7 6-2 0-6 6-2. Il 26enne è così diventato il primo cinese della storia a battere un top 5 della classifica ATP.
Rientrata qualche settimana fa alle competizioni dopo una pausa di tre anni, la ex numero uno al mondo Caroline Wozniacki (WTA 623) ha invece firmato l'impresa in campo femminile contro Petra Kvitova (11). Già finalista a New York nel 2009 e 2014, la danese si è imposta in due set per 7-5 7-6 (7/5) in 2h10', regalandosi così la sfida al terzo turno contro la padrona di casa Jennifer Brady (433).
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