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Curare il diabete e l’obesità disattivando una proteina? Uno studio dell’Università cattolica di Loubain, in Belgio, ha dimostrato che è possibile.
La proteina in questione, che ha un ruolo nella regolazione del peso corporeo, è la MyD88 e fa parte del sistema immunitario dell’intestino; si è scoperto che la sua disattivazione permette di consumare più energia, perdere peso e diminuire al contempo il diabete di tipo 2.
I ricercatori hanno reso dei topi obesi e diabetici con una dieta ricca di grassi. Poi hanno indotto una mutazioni per disattivare la MyD88 e osservato le modificazioni del sistema immunitario dell'intestino: hanno così verificato che era possibile controllare il consumo energetico e rallentare lo sviluppo del tessuto adiposo, riducendo l'infiammazione presente nell'obesità e proteggendo contro il diabete di tipo 2.
L’applicazione sull’uomo è ancora lontana, ma la scoperta dimostra come il sistema immunitario intestinale svolge un ruolo nella regolazione del peso.
ATS/ludoC
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